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Strattice™ Reconstructive Tissue Matrix

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Strattice™ Reconstructive Tissue Matrix is a sterile reconstructive tissue matrix that supports tissue regeneration. Derived from porcine dermis, it undergoes LifeCell’s non-damaging proprietary processing that removes cells and significantly reduces the key component believed to play a major role in the xenogeneic rejection response1.

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In a primate model, Strattice™ Tissue Matrix demonstrated rapid revascularization, cell repopulation and white cell migration as early as two weeks post implantation and mature vascular structure at six months post implantation. Strattice™ Tissue Matrix is recommended for use in soft tissue reinforcement, including hernia repair and breast reconstruction. Its benefits include:

Challenging hernia repair

  • Provides for strong repair2 - Strattice™ Tissue Matrix offers excellent biomechanical strength.
  • Minimizes adhesions to implant3- Strattice™ Tissue Matrix minimizes hernia repair complications and allows for simpler future surgeries in the abdominal are

Breast reconstruction postmastectomy

  • Optimizes aesthetic results - Strattice™ Tissue Matrix provides additional tissue for implant coverage in cases of aggressive resection; helps control implant location; helps define the inframammary and lateral mammary folds; may help hide implant visibility; and creates a more natural-looking breast.
  • May minimize the risk of some complications - Strattice™ Tissue Matrix may help mask breast implant palpability; helps prevent bottoming out or extrusion of implant; may help to prevent skin flap thinning and pectoralis major muscle retraction; and eliminates the need to elevate the serratus muscle.
  • Controls breast implant location - Strattice™ Tissue Matrix acts as an "internal bra" to support the implant and helps the surgeon control the pocket size.
  • Supports fold malposition repairs - Strattice™ Tissue Matrix may be used to redefine and support a new fold inferiorly or laterally.
  • Masks appearance of implant wrinkles or ripples - Strattice™ Tissue Matrix can support the implant, control the pocket size and minimise visible wrinkles, ripples and irregular contours.

Watch an animation on Breast Reconstruction Post Mastectomy with Strattice™ Reconstructive Tissue Matrix

1. Connor J, et al. Retention of structural and biochemical integrity in a biologic mesh supports tissue remodeling in a primate abdominal wall model. Regen Med. 2009;4(2):185-195.
2 Benchtop data on file.
3. Burns NK, et al. Non-cross linked porcine acellular dermal matrices for abdominal wall reconstruction. Plast Reconstr Surg. 2009:PMID:19910855.

Before use, physicians should review all risk information and essential prescribing information which can be found in the Strattice™ Reconstructive Tissue Matrix Instructions for Use (PDF, 4 MB)

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